Filadelfia DICE 2024

The 6th Dianalund International Conference on Epilepsy 

Looking forward to welcoming you at  Hotel Køge Strand in may 2- 3th 2024.

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 Introduction

It is our great pleasure to invite you to the 6th Dianalund International Conference on Epilepsy. The topic of the conference is: “Overlapping clinical phenotypes in monogenic epilepsies – common molecular pathways?”

Introduction
Amongst many genetic epilepsies and epileptic encephalopathies, the phenotypic spectrum can be broad (evenin patients with identical genetic alterations) and genetic modifiers are typically implicated. Despite their different genetic etiologies, patients can have seemingly similar clinical presentations. For example, SCN1A-related disorders can clinically overlap with other genetic diseases such as those which are GABAA-receptor-related. Then there are various comorbidities – for instance, movement disorders – which can also have features which overlap with those of other conditions. It has been suggested that the comorbidities of distinct phenotypes may reflect an overlap of both the causative genes and the involvement of similar molecular processes for these disorders. It is clear that the study paradigms required to successfully address these questions are lacking and therefore require further research.

At the conference
We shall review current knowledge on the phenotypic expressions, their overlapping features, and the genotype-phenotype correlations of some epileptic disorders and epileptic encephalopathies. With an aim to guide the discovery and development of effective targeted treatments, we shall discuss possible underlying and shared pathophysiological mechanisms and molecular substrates and then present both the emerging concepts in the field of precision medicine and the yields of the most advanced research strategies. The conference will conclude with evidence and case presentations from the audience which, based on the understanding of underlying genetic anomalies, support the role of novel treatments.

Conference venue
Comwell Køge Strand, Strandvejen 111, 4600 Køge (Denmark).

Rooms are available for the participants at Comwell Køge strand and can be included in the registration. 

Registration fees:

€ 500: Full meeting incl. conference dinner (2/5-2024), 2 nights (1-3/5-2024) welcome reception (1/5-2024)

€ 400: Full meeting incl. conference dinner (2/5-2024), 1 night (2-3/5-2024)

€ 300: Full meeting incl. conference dinner (2/5-2024)

€ 100: One day registration

Looking forward to welcoming you in Denmark.

For questions please contact us at: dice@filadelfia.dk  

Best wishes

Rikke Møller, Elena Gardella, Guido Rubboli